Keynote Address

Ron Germain
National Institute of Allergy and Infectious Disease
Imaging the immune system - visualizing how the immune system really works

Symposium I − cancer immunology and immunotherapy

Carl June
University of Pennsylvania
T cell therapy for cancer

Chrystal Paulos
Medical University of South Carolina
"Juicing" T cells with small molecules to enhance long-lived memory responses to tumors

Christopher Klebanoff
Memorial Sloan Kettering Cancer Center
"Insulating" adoptively transferred T cells from a hostile tumor environment

Miriam Merad
Icahn School of Medicine at Mt. Sinai
Myeloid cell contribution to tumor outcome

Symposium II − Epigenetics and immunity

Benjamin Youngblood
St. Jude's Children's Research Hospital
Epigenetic regulation of memory T cell differentiation and exhaustion

Ananda Goldrath
University of California, San Diego
Transcriptional regulation directing T cell differentiation

Steve Smale
University of California, Los Angeles
Selective regulation of stimulus-induced transcription

Anjana Rao
La Jolla Institute of Allergy and Immunology
Epigenetic and transcriptional programs in T and B cells

Symposium III − T Cell development and maturation

Kristin Hogquist
University of Minnesota
Thymic selection of soldiers and peacekeepers

Pam Fink
University of Washington
Recent thymic emigrant function - defective or adaptive?

Ellen Rothenberg
California Institute of Technology
Gene networks that trigger the start of T cell development

Virginia Smith Shapiro
Mayo Clinic
Epigenetic regulation of thymocyte positive selection and lineage commitment


Keynote Address

David Oshinsky
New York University
Polio: A look back at America's most successful public health crusade

Symposium I − Host response during chronic infections

JoAnne Flynn
University of Pittsburgh
Tracking granulomas to reveal early and late events in tuberculosis

Alan Sher
National Institutes of Health
Regulation of CD4+ T cell effector function in Toxoplasma infection

David Brooks
Princess Margaret Cancer Center, Toronto
Inflammation and immunosuppression in persistent infections

Dorian McGavern
National Institutes of Health
Dynamics of dysfunctional T and B cell responses during persistent viral infection

Symposium II − New vaccine approaches: Targeting old enemies

Marty Moore
Emory University
Fifty-Valent inactivated rhinovirus vaccine

Ralph Baric
University of North Carolina
Dengue virus structure-guided immunogen design

Galit Alter
Massachusetts General Hospital
Systems serology: A new approach for defining vaccine correlates and mechanisms of protection.

James Crowe
Vanderbilt University
Canonical modes of recognition of diverse viruses by human neutralizing antibodies

Symposium III − Immune responses in the lung

Clare Lloyd
Imperial College, London
Living on the edge - Regulation of pulmonary immunity by epithelial cells

Thomas Braciale
University of Virginia
Innate immune control of respiratory virus infection

Nicholas Lukacs
University of Michigan
Alteration of respiratory immune responses by RSV infection

Steve Varga
University of Iowa
Failed memory to respiratory syncytial virus


Keynote address

Mario Capecchi
University of Utah
Gene Targeting into the 21st Century: Mouse Models of Human Disease from Cancer to Neuropsychiatric Disorders

Symposium I − T helper cell function: A polarizing response

Mark Kaplan
Indiana University
ETS transcription factors in the development of Th9 cells

John O'Shea
National Institutes of Health
Lymphocyte Genomic Switches: Helping lymphocytes to understand themselves and their potential

Amy Weinmann
University of Alabama, Birmingham
Metabolism and T cell differentiation states

Shabaana Khader
Washington University
The tubercle granuloma: To be, or not to be.

Symposium II − Immunoregulation

Michael Farrar
University of Minnesota
Regulatory T cell development and function

Maria-Grazia Roncarolo
Stanford University
T regulatory cell therapy: from bench to bedside and back

Thomas Tedder
Duke University
Regulatory B10 cell development, function, and application to disease

Paulo Rodriguez
Georgia Regents University
Cellular stress checkpoints regulate the function and accumulation of Myeloid-derived suppressor cells (MDSC) in tumors

Symposium III − Broadly neutralizing antibodies

Pamela Bjorkman
California Institute of Technology
A Molecular Arms Race: The Immune System Versus HIV

George Georgiou
University of Texas, Austin
Molecular analysis of the serum antibody repertoire elucidates the humoral response to the seasonal flu vaccine

Florian Krammer
Mount Sinai
Broadly protective influenza virus vaccines based on cross-reactive antibodies to the viral surface glycoproteins

Patrick Wilson
University of Chicago
Targeting conserved influenza epitopes

Workshop block I

Allergy and Asthma I
Ian Lewkowich
Cincinnati Children's Hospital

Autoimmunity I
William Carson
University of Michigan

B cell development
Kay Medina
Mayo Clinic

Immune response to bacteria and parasites I
Lin-Xi Li
University of Arkansas for Medical Sciences

Immune response to viruses I
Ryan Langlois
University of Minnesota

Inflammatory Processes I
David Feola
University of Kentucky

Innate Immunity
Kerry Empey
University of Pittsburgh

Tumor Immunology I
Ryan Teague
St Louis University

Workshop block II

Allergy and Asthma II
Jane Schuh
North Dakota State University

Autoimmunity II
Marcia McInerney
University of Toledo

Immune response to bacteria and parasites II
Steve Templeton
Indiana University, Indianapolis

Immune response to viruses II
Vladimir Badovinac
University of Iowa

Inflammatory Processes II
Kamalakannan Rajasekaran
BloodCenter of Wisconsin

Lymphocyte Activation and Signaling
Diana Gil Pages
Mayo Clinic

T cell development
Fotini Gounari
University of Chicago

T cell subsets
Charlotte Vines
University of Texas, El Paso

Transplantation and Tolerance
Richard DiPaolo
St Louis University

General meeting information

Meeting chaired by: Michael Farrar, University of Minnesota, Minneapolis
Meeting location: Chicago Marriott Downtown, Chicago, Illinois
Abstracts presented: 187
Trainees: $125
Investigators: $200